Comparison of the prevalence of metabolic syndrome and its association with diabetes and cardiovascular disease in the rural population of Bangladesh using the modified National Cholesterol Education Program Expert Panel Adult Treatment Panel III and International Diabetes Federation definitions |
| |
| Authors: | Bishwajit Bhowmik Faria Afsana Tasnima Siddiquee Sanjida B Munir Fareeha Sheikh Erica Wright Farjana R Bhuiyan Sheikh Mohammad Ashrafuzzaman Hajera Mahtab Abul Kalam Azad Khan Akhtar Hussain |
| |
| Affiliation: | 1. Department of Community Medicine, Institute of Health and Society, University of Oslo, Oslo, Norway;2. Department of Endocrinology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh;3. Executive Diabetes Care Center, NHN, Diabetic Association of Bangladesh, Dhaka, Bangladesh;4. ACT Diabetes Service, Division of Medicine, Canberra Hospital, Canberra, Australia;5. Department of Biochemistry & Cell Biology, Bangladesh University of Health Sciences (BUHS), Dhaka, Bangladesh |
| |
| Abstract: | Aims/IntroductionTo compare the prevalence of metabolic syndrome (MS) using the modified National Cholesterol Education Program Adult Treatment Plan III (NCEP) and the International Diabetes Federation (IDF) definitions and, using both definitions, determine and compare the association of MS, prediabetes, type 2 diabetes, hypertension (HTN) and cardiovascular disease risk (CVD).Materials and MethodsA total of 2,293 randomly selected participants (aged ≥20 years) in a rural community in Bangladesh were investigated in a population-based cross-sectional study. Sociodemographic and anthropometric characteristics, blood pressure, blood glucose, and lipid profiles were studied. Age-adjusted data for MS and cardiometabolic risk factors were assessed, and their relationships were examined.ResultsThe age-adjusted prevalence of MS was 30.7% (males 30.5%; females 30.5%) using the NCEP definition, and 24.5% (males 19.2%, females 27.5%) using the IDF definition. The prevalence of MS using the NCEP definition was also higher in study participants with prediabetes, type 2 diabetes, HTN and CVD risk. The agreement rate between both definitions was 92% (k = 0.80). The NCEP definition had a stronger association with type 2 diabetes and HTN (odds ratio 12.4 vs 5.2; odds ratio 7.0 vs 4.7, respectively) than the IDF definition. However, the odds ratios for prediabetes and CVD risk were not significantly different.ConclusionsThe prevalence of MS was higher using the NCEP definition, and was more strongly associated with prediabetes, type 2 diabetes, HTN and CVD in this Bangladeshi population. |
| |
| Keywords: | Bangladeshi population Diabetes Metabolic syndrome |
|
|
