| 东亚钳蝎毒抗癫痫肽作用机制研究 |
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| 引用本文： | 于家琨,张景海,王起振,刘崇铭.东亚钳蝎毒抗癫痫肽作用机制研究[J].沈阳药科大学学报,1993(1). |
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| 作者姓名： | 于家琨 张景海 王起振 刘崇铭 |
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| 作者单位： | 北京第三制药厂研究所
(于家琨)，沈阳药学院生理学教研室
(张景海)，沈阳药学院生物化学教研室
(王起振)，沈阳药学院生物化学教研室(刘崇铭) |
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| 基金项目： | 1987～1989国家青年自然科学基金 |
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| 摘 要： | 本文用整体大鼠和猫隔离皮层,研究了东亚钳蝎毒抗癫痫肽(AEP)的抗癫痫作用机制。实验表明,AEP的抗癫痫作用依赖于单胺类神经递质的存在。
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| 关 键 词： | 东亚钳蝎毒 抗癫痫肽 猫隔离皮层 单胺类神经递质 |
A STUDY ON THE MECHENISM OF AEP PURIFIED FROM VENOM OF BUTHUS MARTENSII KARSCH |
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| Yu Jiakun Liu chongming Zhang Jinghai Wang Qizhen Dept.of Physiol. Dept.of Biochem..A STUDY ON THE MECHENISM OF AEP PURIFIED FROM VENOM OF BUTHUS MARTENSII KARSCH[J].Journal of Shenyang Pharmaceutical University,1993(1). |
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| Authors: | Yu Jiakun Liu chongming Zhang Jinghai Wang Qizhen Deptof Physiol Deptof Biochem |
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| Institution: | Yu Jiakun Liu chongming Zhang Jinghai Wang Qizhen Dept.of Physiol. Dept.of Biochem. |
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| Abstract: | The mechenism of antiepilepsy (AEP) purified from the venom of butbus martensii karscb was studied in unanesthetized rats and isolated cortex of unanesthethetized cats. It is suggested that the effect of AEP relies on the existence of mono-amino transmitters in brain. |
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| Keywords: | Venom of buthus martensii karsch Anti-epilepsy peptide Cat isolated cortex Mono-amino transmitter |
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