RENAL COMPENSATORY HYPERTROPHY IN CHILDREN WITH UNILATERAL RENAL DISEASE |
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Authors: | P WILTON A APERIA O BROBERGER I WIKSTAD |
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Institution: | Departments of Paediatrics and Paediatric Radiology, Karolinska Institute, St. Göran's Children's Hospital, Stockholm, Sweden |
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Abstract: | Abstract. Wilton, P., Aperia, A., Broberger, O. and Wikstad, I. (Departments of Pediatrics and Pediatric Radiology, Karolinska Institute, St. Göran's Children's Hospital, Stockholm, Sweden). Renal compensatory hypertrophy in children with unilateral renal disease. Acta Paediatr Scand, 69:83, 1980.—Kidney parenchymal size was estimated on urograms from 22 children with unilateral vesico-ureteral reflux (VUR), 14 children with bilateral VUR and seven children with unilateral heminephrectomy. In the bilateral VUR group, one kidney was roentgenologically normal and the other was growth-retarded. The GFR was estimated in 19 of the children. The age of the children was 3–17 years and all had a history of urinary tract infection. The size of the smaller kidney varied between 33–97% of normal. Children in the unilateral VUR group with a small kidney due to scarring and/or growth retardation showed a varying degree of compensatory hypertrophy in the contra-lateral kidney, which was proportional to the parenchymal reduction. This compensation was inhibited in the bilateral VUR group. There was a positive correlation between the GFR and kidney size |
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Keywords: | enal hypertrophy vesico-ureteral reflux kidney size renal function heminephrectomy |
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