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刺茎楤木根皮抗炎和免疫作用的研究
引用本文:肖本见,谭志鑫,梁文梅. 刺茎楤木根皮抗炎和免疫作用的研究[J]. 中国现代应用药学, 2006, 23(6): 438-440
作者姓名:肖本见  谭志鑫  梁文梅
作者单位:1. 湖北民族学院医学院,湖北,恩施,445000
2. 湖北施恩堂制药有限公司,湖北,恩施,445000
摘    要:目的探讨刺茎楤木根皮的抗炎和免疫作用。方法抗炎实验采用巴豆油致小鼠耳廓肿胀等常规抗炎模型;免疫实验采用对小鼠体内碳粒廓清功能影响等的方法。结果刺茎楤木根皮提取物可明显抑制巴豆油致小鼠耳廊肿胀及角叉菜胶引起的大鼠足跖肿胀,能明显抑制大鼠棉球肉芽肿的增重及2,4二硝基氯苯(DNCB)致小鼠迟发型超敏反应(DTH),增强吞噬功能。结论刺茎楤木根皮有明显的抗炎和免疫调节作用。

关 键 词:刺茎楤木  抗炎作用  免疫功能
文章编号:1007-7693(2006)06-0438-03
收稿时间:2005-06-29
修稿时间:2005-06-29

Studies on anti-inflammatory and immune effect of root bark of Aralia echinocaulis
XIAO Ben-jian~(,TAN Zhi-xin~(,LIANG Wen-mei~(. Studies on anti-inflammatory and immune effect of root bark of Aralia echinocaulis[J]. The Chinese Journal of Modern Applied Pharmacy, 2006, 23(6): 438-440
Authors:XIAO Ben-jian~(  TAN Zhi-xin~(  LIANG Wen-mei~(
Affiliation:1. The Medical School ofHubei Instiutefor Nationalities, Enshi 445000, China; 2. Hubei Shientang pharmaceutical Co. LTD , Enshi 445000, China
Abstract:OBJECTIVE To study the anti-inflammatory and immune effects of root bark of Aralia echinocaulis.METHODS A few conventional models,such as the mouse pinna swelling induced by cotton oil carbo clearance in mice were applied. RESULTS Root bark of Aralia echinocaulis obviously inhibited the swelling of mouse pinna induced by croton oil,suppressed the edema of rat hind paw swelling elicited by injection of 1% carrageenan,significantly depressed the increase of proliferation of granuloma led by implanting cotton pellet and the deleyed-type hypersensitivity delayed type hypereneitivity(DTH) reactions reduced by DNCB,It increased phagocytosis function.CONCLUSION Root bark of Aralia echinocaulis has the effects of anti-inflommatory and immune regulation.
Keywords:Aralia echinocaulis  anti-inflammatory effects  immunefunction  
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