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Switch from cytology-based to human papillomavirus test-based cervical screening: implications for colposcopy |
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| Authors: | Porras Carolina Wentzensen Nicolas Rodríguez Ana C Morales Jorge Burk Robert D Alfaro Mario Hutchinson Martha Herrero Rolando Hildesheim Allan Sherman Mark E Wacholder Sholom Solomon Diane Schiffman Mark |
| Institution: | Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA. cporras@proyectoguanacaste.org |
| Abstract: | Human papillomavirus (HPV) testing is more sensitive than cytology; some cervical cancer prevention programs will switch from cytology to carcinogenic HPV test-based screening. The objective of our study is to evaluate the clinical implications of a switch to HPV test-based screening on performance and workload of colposcopy. Women in the population-based, 7-year Guanacaste cohort study were screened at enrollment using cytology. We also took another specimen for HPV DNA testing and collected magnified cervical photographic images (cervigrams). A final case diagnosis (≥cervical intraepithelial neoplasia CIN] grade 3, CIN2, |
| Keywords: | HPV testing cytology colposcopy cervical cancer screening cervicography |
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