| 白酒草中2个新的三萜皂苷 |
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| 引用本文： | 颜世伦,苏艳芳,解笑瑜,郭成云,阙 梦,陈 磊. 白酒草中2个新的三萜皂苷[J]. 中草药, 2014, 45(1): 23-27 |
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| 作者姓名： | 颜世伦 苏艳芳 解笑瑜 郭成云 阙 梦 陈 磊 |
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| 作者单位： | 1.天津大学药物科学与技术学院 天津市现代药物传递及功能高效化重点实验室，天津 300072 2.天津中医药大学 天津市中药化学与分析重点实验室，天津 300193 3.天津天士力现代中药资源有限公司，天津 300410 |
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| 基金项目： | 新世纪优秀人才支持计划资助项目（NCET-09-0589）；天津市科技支撑计划国际科技合作项目（11ZCGHHZ00800） |
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| 摘 要： | 目的 研究白酒草Conyza japonica全草的皂苷类成分。方法 采用D101大孔吸附树脂、硅胶、ODS和RP-HPLC对白酒草乙醇提取物中的皂苷类成分进行分离纯化，并应用波谱分析及酸水解方法鉴定其结构。结果 从白酒草全草的乙醇提取物中分离鉴定了2个三萜皂苷类化合物，分别命名为白酒草皂苷R（1）和白酒草皂苷S（2）。结论 化合物1和2为新的三萜皂苷，2个新化合物28位糖链均含有2个芹糖，在天然化合物中非常少见。
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| 关 键 词： | 白酒草；三萜皂苷；白酒草皂苷R；白酒草皂苷S；芹糖 |
Two new triterpenoid saponins from Conyza japonica |
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| YAN Shi-lun,SU Yan-fang,XIE Xiao-yu,GUO Cheng-yun,QUE Meng,CHEN Lei. Two new triterpenoid saponins from Conyza japonica[J]. Chinese Traditional and Herbal Drugs, 2014, 45(1): 23-27 |
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| Authors: | YAN Shi-lun SU Yan-fang XIE Xiao-yu GUO Cheng-yun QUE Meng CHEN Lei |
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| Affiliation: | 1.Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China 2.Tianjin Key Laboratory of TCM Chemistry and Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 3.Tianjin Tasly Modern TCM Resources Co., Ltd., Tianjin 300410, China |
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| Abstract: | Objective To study the triterpenoid saponins from Conyza japonica. Methods The triterpenoid saponins from C. japonica were isolated and purified by chromatography over resin D101, silica gel, ODS columns, and RP-HPLC. The structures were elucidated on the basis of spectroscopic analysis and acid hydrolysis. Results Two new triterpenoid saponins were isolated and named as conyzasaponin R (1) and conyzasaponin S (2). Conclusion Compounds 1 and 2 are new triterpenoid saponins, and they are among the few examples of natural products bearing two apoise units in a single oligosaccharide chain. |
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| Keywords: | Conyza japonica (Thunb.) Less. triterpenoid saponins conyzasaponin R conyzasaponin S apoise |
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