胃肠道功能与急性胰腺炎病情严重程度的关系

目的探讨胃肠道功能与急性胰腺炎病情严重程度的关系。方法回顾性总结我科2001年9月-2012年8月成功救治的42例急性胰腺炎患者的临床资料。将患者胃肠道功能按严重程度进行评分,同时评测患者入院当天的急性生理及慢性健康状况评分Ⅱ（acute physiology and chronic health evaluationⅡ,APACHEⅡ）和CT严重度指数（computer tomography severityindex,CTSI）评分,将胃肠道功能中重度不良天数与ICU住院天数、呼吸机使用天数进行相关性分析。比较胃肠道中重度不良组与轻度不良组中重症患者比例。结果急性胰腺炎患者的胃肠道功能不良评分越高,其APACHEⅡ评分（r=0.612,P=0.028）和CTSI评分（r=0.477,P=0.006）也越高,且ICU住院天数（r=0.640,P=0.035）及呼吸机使用天数（r=0.779,P=0.022）与胃肠道功能中重度不良天数呈正相关。胃肠道中重度不良患者中重症胰腺炎比例更高（χ2=4.367,P=0.037）。结论胃肠道功能可反映急性胰腺炎患者病情严重程度。

Relation between gastrointestinal function and severity of acute pancreatitis

Objective To study the relation between gastrointestinal function and severity of acute pancreatitis.Methods Clinical data about 42 patients with acute pancreatitis admitted to our department from September 2001 to August 2012 were retrospectively analyzed.Their gastrointestinal function and acute physiology and chronic health were scored according to the acute physiology and chronic health evaluationⅡ（APACHEⅡ）,computer tomography severity index（CTSI） on the day they were admitted.Correlation of the days of moderate-severe gastrointestinal malfunction with the hospital stay days in ICU and the days of mechanical ventilation was analyzed.The proportion of severe patients with moderate-severe gastrointestinal malfunction and those with mild gastrointestinal malfunction was compared.Results The higher the gastrointestinal malfunction score was,the higher the APACHEⅡ score and CTSI score were in patients with acute pancreatitis（r=0.612,P=0.028;r=0.477,P=0.006）.The hospital stay days and mechanical ventilation days were positively related with the days of moderate-severe gastrointestinal malfunction（r=0.640,P=0.035;r= 0.779,P=0.022）.The proportion of severe patients with moderate-severe gastrointestinal malfunction was higher than that of those with mild gastrointestinal malfunction（χ2=4.367,P=0.037）.Conclusion Gastrointestinal function can predict the severity of acute pancreatitis.