Comparative results of central corneal thickness measurements in primary open-angle glaucoma, pseudoexfoliation glaucoma, and ocular hypertension.

BACKGROUND AND OBJECTIVE: As clinical measurements of corneal thickness have become widely available, several studies found a positive correlation between central corneal thickness and applanation tonometry measurements. This study evaluated central corneal thickness in different types of glaucoma. PATIENTS AND METHODS: An observational cross-sectional study assessed central corneal thickness using a specular microscope in the following groups of patients: 60 eyes with primary open-angle glaucoma, 50 eyes with pseudoexfoliation glaucoma, 50 eyes with ocular hypertension, and 60 eyes without glaucoma or ocular hypertension (control group). RESULTS: Central corneal thickness was significantly thinner in cases with pseudoexfoliation glaucoma (P < .0001) and significantly thicker in cases with ocular hypertension (P< .0001). CONCLUSIONS: These results agree with the literature, strengthening the position that central corneal thickness varies in different types of glaucoma and, therefore, is a parameter that should be taken under consideration, especially when evaluating cases of pseudoexfoliative glaucoma and ocular hypertension.