Genetic diversity and haplotype analysis of Guizhou Miao identified with 19 X-chromosomal short tandem repeats |
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Authors: | Han Yanyan He Guanglin Gong Sheng Chen Junying Jiang Zhigang Chen Pengyu |
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Institution: | 1.School of Public Health, Zunyi Medical University, Zunyi, 563099, Guizhou, China ;2.Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 610041, Sichuan, China ;3.Criminal Investigation Detachment, Qianxinan Prefecture Public Security Bureau, Xingyi, Guizhou, China ;4.Judicial Expertise Center, Zunyi City Public Security Bureau, Zunyi, 563099, Guizhou, China ;5.Center of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, 563099, Guizhou, China ;6.School of Forensic Medicine, Zunyi Medical University, Zunyi, 563099, Guizhou, China ; |
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Abstract: | We analyzed Chinese Miao population samples (n = 268) from Guizhou province, Southwest China, with 19 X-chromosomal short tandem repeats (STRs) included in the AGCU X19 amplification kit. The combined PE is 0.999999922 and the combined PDs in males and females are 0.9999999999999999999994 and 0.9999999999998, respectively. The mean paternity exclusion change values are larger than 0.99999996. The HDs in seven linkage groups vary from 0.9324 to 0.9968. Subsequently, comparison among different Chinese populations shows that the substructures of Chinese were significantly influenced by ethno-linguistic rather than geographical boundaries, including most prominently Turkic-speaking and Tibeto-Burman-speaking populations. |
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