基于Matlab精确测量半规管在颅底中的方位

目的:确定半规管在颅底的精确方位,并分析其在不同年龄组、侧别和性别中的差异.方法:将45例正常人(90侧耳)的CT序列图像导入Mimics软件,读取确定半规管平面的标志点以及为确定以法兰克福平面为基准的标准空间坐标系的关键结构标志点的三维坐标,基于Matlab软件编制计算程序Laby Calculation,确定标准空间坐标系的相关方程,计算半规管在标准坐标系中的空间方位和面面夹角,最后对数据进行统计分析.结果:半规管的方位在不同年龄组和性别中具有一定的差异,而左右侧无明显差异,不同年龄组同侧半规管间面面夹角比较差异均无统计学意义(p＞0.05),提示随年龄增长同侧三个半规管方位的旋转可能是作为一个整体一同发生的.结论:本研究可为半规管发育研究提供形态数据,并对相关前庭功能检查和平衡功能障碍治疗提供依据和帮助.

Accurate Measurement of Planer Orientation of Semicircular Canals in Skull Base Based on Matlab Software

Objective：To measure accurate planer orientations of semicircular canals in skull base and to analyze their ages, sides and sex differences. Methods： CT serial images of 45 normal people （ 90 ears） were imported into Mimics software for image processing. Three - dimensional coordinate values of landmarks of the semicircular canals and key structures which were used to define a standard three - dimensional coordinate system based on the Frankfurt horizontal plane. And then, the standard plane equations were obtained by a self - developed calculation program, LabyCalculation, with the support of Matlab software. The spatial orientations of the semicircular canals and angles among the semicircular canals in this new coordinate system were calculat- ed. Finally, the data were analyzed statistically. Results：The results showed that semicircular canals＇ orienta- tions in skull base had certain differences in different sexes and age groups, yet without obvious differences be- tween both sides. The angles between ipsilateral semicircular canals among different age groups showed no sta- tistically significant difference, and it suggested that the orientations of ipsilateral three semicircular canals could change as a whole with age. Concinsions：Our research can provide some help for ear development study,vestibular function testing and treatment of vestibular dysfunction.