| 胆固醇结石病的发生机制 |
| |
| 引用本文： | 蒋兆彦,韩天权,张圣道.胆固醇结石病的发生机制[J].世界华人消化杂志,2010,18(12). |
| |
| 作者姓名： | 蒋兆彦 韩天权 张圣道 |
| |
| 作者单位： | 上海交通大学医学院附属瑞金医院外科,上海消化外科研究所,上海市,200025 |
| |
| 基金项目： | 国家自然科学基金，上海市重点学科-外科学基金资助项目 |
| |
| 摘 要： | 胆石病是常见病,患病率在10%左右.近期,胆固醇结石病与代谢综合征,肠肝轴脂质代谢异常受到关注.本文论述胆固醇结石发病机制的研究领域中有关胆汁胆固醇的主要来源,肠道吸收胆固醇,胆囊运动的调节,胆固醇的载体以及代谢综合征的进展,并提出胆囊结石病基础研究的若干任务.
|
| 关 键 词： | 胆固醇结石病 肝脏 小肠 胆囊 发病机制 |
Pathogenesis of cholesterol gallstone disease |
| |
| Zhao-Yan Jiang,Tian-Quan Han,Sheng-Dao Zhang.Pathogenesis of cholesterol gallstone disease[J].World Chinese Journal of Digestology,2010,18(12). |
| |
| Authors: | Zhao-Yan Jiang Tian-Quan Han Sheng-Dao Zhang |
| |
| Institution: | Zhao-Yan Jiang,Tian-Quan Han,Sheng-Dao Zhang,Department of Surgery,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai Institute of Digestive Surgery,Shanghai 200025,China |
| |
| Abstract: | Cholesterol gallstone disease is a common disorder with an incidence rate of about 10%.In recent years,the research on metabolic disorders involving the gut-liver axis and the relation between gallstone disease and metabolic syndrome is attracting more attention.This article focuses on the origin of biliary cholesterol,intestinal cholesterol absorption,regulation of gallbladder motility,cholesterol transporters and metabolic syndromes and their role in the pathogenesis of gallstone disease. |
| |
| Keywords: | Cholesterol gallstone disease Liver Small intestine Gallbladder Pathogenesis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
