| 筛检不规则抗体在输血的临床应用研究 |
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| 引用本文： | 危艳顺,姚明.筛检不规则抗体在输血的临床应用研究[J].海南医学院学报,2013,19(3):401-403. |
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| 作者姓名： | 危艳顺 姚明 |
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| 作者单位： | 湖北省鄂州市鄂钢医院检验科,湖北鄂州,436002 |
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| 基金项目： | 中国高校医学期刊临床专项资金项目 |
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| 摘 要： | 目的:研究不规则抗体的检测在输血治疗过程中的临床应用价值。方法:采用卡式微柱凝胶法检测2 590例输血患者(观察组)的不规则抗体,分析不规则抗体的分布情况,并以1 346例未进行不规则抗体的输血患者为对照组,比较两组的输血反应发生率。结果:观察组不规则抗体检测阳性率10.03‰(26/2 590),其中抗-E抗体3.86‰、抗-D抗体2.32‰;不规则抗体的产生与妊娠及多次输血有关,行不规则抗体筛查的观察组输血反应发生率为1.16‰,与对照组输血反应发生率3.71‰经卡方检验分析,有统计学差异(P<0.05)。结论:妊娠与多次输血是不规则抗体产生的主要原因之一,输血前不规则抗体的筛查有利于安全用血。
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| 关 键 词： | 不规则抗体 微柱凝胶法 输血 |
Clinical application value of irregular antibody detection in transfusion therapy |
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| Abstract: | Objective:To study the clinical application value of irregular antibody detection in transfusion therapy.Methods:Detected irregular antibodies in 2 590 patients underwent blood transfusion(Study group) using card micro column gel method,analyzed irregular antibodies distribution.Transfusion reaction rate of those patients were compared with another 1 346 cases that hadn't underwent irregular antibodies detection.Results:Positive rate of irregular antibody was 10.03‰(26/2590) in the observation group,of which the anti-E was 3.86‰,anti-D was 2.32 ‰.Irregular antibodies were associated with pregnancy and multiple blood transfusions.The observation group blood transfusion reaction rate was 1.16‰,and the control group blood transfusion reaction rate3.71 ‰,chi-square analysis revealed significant difference(P<0.05).Conclusion:Pregnancy,multiple blood transfusions are primary causes that produce irregular antibody,and screening of irregular antibody is helpful for the safety of blood transfusion |
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| Keywords: | Irregular antibodies Microcolumn gel method Blood transfusion |
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