微生态制剂在高胆红素血症新生儿中的应用

目的 探讨微生态制剂对新生儿高胆红素血症的治疗效果.方法 研究对象为2011年6月至2012年6月我院收治的82例新生儿高胆红素血症患儿,随机分为治疗组（对照组的基础上服用双歧三联活菌制剂）及对照组（基础治疗和蓝光治疗）,每组41例.比较分析治疗前后患儿血清胆红素量及黄疸消退时间.结果 治疗后血清中总胆红素水平治疗组显著低于对照组（184.3μmol/Lvs 256.7μmol/L,P＜0.05）;治疗组黄疸消退时间显著短于对照组（25.1 h vs 39.8 h,P＜0.05）;治疗组总有效率显著高于对照组（93.5％ vs 64.5％,P＜0.05）.结论 微生态制剂治疗新生儿高胆红素血症,可显著提高疗效,值得临床上推广应用.

Application of micro-ecological agents on newborn hyperbilirubinemia

Objective To investigate the therapeutic effect of micro-ecological agents on premature hyperbilirubinemia.Methods 82 newborn infants with hyperbilirubinemia was studied,which were divided into treatment group （given bifid triple viable-preparation on the basis therapy of control group,41 cases） and control group （took basic treatment and blue light treatment,41 cases）.The content of serum bilirubin and aundice subsidise time of the two groups before and after treatment were observed and detected.Results After treatment,the total serum bilirubin of the two groups showed no significant difference （184.3 μ mol/L vs 256.7 μ mol/L,P〈0.05）,the aundice subsidise time of the treatment group decreased obviously compared with that of control （25.1 hours vs 39.8 hours,P〈0.05）.The total effective rate in treatment group was significant higher than that in control group （93.5% vs 64.5%,P〈0.05）.Conclusion Micro-ecological agents used as treatment for newborn hyperbilirubinemia can significantly improve therapeutic effect,and worthy of clinical application promotion.