The progressive nature of subaortic stenosis in congenital heart disease |
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| Authors: | R M Freedom A Pelech A Brand M Vogel P M Olley J Smallhorn R D Rowe |
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| Affiliation: | 1. Division of Cardiology, Department of Pediatrics, The Hospital for Sick Children, and Departments of Pediatrics and Pathology, The University of Toronto Faculty of Medicine Canada;2. Division of Cardiology, Department of Pathology, The Hospital for Sick Children, and Departments of Pediatrics and Pathology, The University of Toronto Faculty of Medicine Canada |
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| Abstract: | Data derived from serial hemodynamic and angiocardiographic investigations on pediatric patients not subjected to intervening intracardiac operations support the view that subaortic stenosis in congenital heart disease tends to be a progressive disorder. Our data are obtained from two groups of patients. The first comprised 22 patients with discrete subaortic stenosis in relative isolation. The second was made up of 19 patients with the fibrous or fibromuscular forms of discrete subaortic stenosis associated with a perimembranous ventricular septal defect. The results from both groups support our initial contention. The progressive character of subaortic stenosis in these two situations illustrates the dynamic nature of congenital heart disease, and the tendency of a changing form and function. |
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| Keywords: | heart defects natural history congenital heart disease ventricular septal defect subaortic diaphragmatic shelf |
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