| 尿铁蛋白测定对某些恶性肿瘤的临床意义 |
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| 引用本文： | 张育,王晓铃.尿铁蛋白测定对某些恶性肿瘤的临床意义[J].实用肿瘤杂志,1991,6(3):148-150. |
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| 作者姓名： | 张育 王晓铃 |
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| 作者单位： | 扬州医学院附院血液科，扬州医学院附院血液科，扬州医学院附院血液科，扬州医学院附院血液科，扬州医学院附院中心实验室，扬州医学院附院中心实验室 |
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| 摘 要： | 本文报道用醇联免疫吸附法(ELISA)测定91侧恶性肿瘤及60名正常人的尿铁蛋白浓度,发现各组恶性肿瘤患者的尿铁蛋白值均高于正常,急性白血病初治、复发组患者在治疗前尿、血铁蛋白呈正相关(Υ=0.638 P<0.001)。急性白血病初治、复发组、恶性淋巴瘤组及其它肿瘤组患者尿铁蛋白值高于正常值上限者分别占84.6%,80.0%和84.0%,而血清铁蛋白则分别为76.9%,60.0%和64.0%。急性白血病治疗前及复发时尿铁蛋白值升高;缓解期下降。尿铁蛋白测定对于恶性肿瘤的诊断及监测白血病化疗效果有一定的临床意义。
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| 关 键 词： | 尿铁蛋白 恶性肿瘤 |
Clinical significance of ferritinuria determination in some tumours |
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| Zhang Yu,et al.Clinical significance of ferritinuria determination in some tumours[J].Journal of Practical Oncology,1991,6(3):148-150. |
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| Authors: | Zhang Yu |
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| Abstract: | Ferritinuria concentration was determined in 91 patients with malignant tumours and 60 controls by ELISA.The results showed that the value of ferritinuria in patients with malignant tumours was higher than that of the normal.A positive correlation was observed between the levels of ferritinuria and serum ferritin in untreated patients and relapsed patients with acute leukemia,The higher levels of ferritinuria than that of the nornal maximum in the groups of untreated patients and relapsed patients with acute leukemia,with malignant lymphma and the group of patients with other malignant tumours were found in 84.6%.80.0% and 84.0% respecti- vely of them,the value of serum ferritin being 76.9%,60.0% and 64.0% respectively.An increased valne of ferritinuria in the untreated and relapsed patients and a decreased one were revealed during remission in patients with acute leukemia.The determination of ferritinuria level was of clinical significance in the diagnosis of malignant tumours and evaluation of treatment of leuke- mia. |
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| Keywords: | ferritinuria malignant tumour |
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