| 陷阱受体3(DcR3)和Fas/FasL系统与消化系肿瘤关系的研究进展 |
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| 引用本文： | 陈张铭,张阳德,任四兰,潘一峰,. 陷阱受体3(DcR3)和Fas/FasL系统与消化系肿瘤关系的研究进展[J]. 中国医学工程, 2007, 15(1): 103-104,106 |
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| 作者姓名： | 陈张铭 张阳德 任四兰 潘一峰 |
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| 作者单位： | 1. 中南大学卫生部肝胆肠外科研究中心,湖南,长沙,410008
2. 长沙医学院,湖南,长沙,410219 |
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| 摘 要： | 陷阱受体3(decoy receptor 3,DcR3)是新发现的一种肿瘤坏死因子超家族成员,研究发现其在多种肿瘤尤其是消化系肿瘤高表达,可能通过与FasL结合干扰Fas/FasL系统介导的细胞凋亡而导致肿瘤发生。研究DcR3和Fas/FasL系统与消化系肿瘤的关系,有助于阐明消化系肿瘤发生发展机制,为消化系肿瘤的治疗提供一种新的思路,并有助于临床合理确定治疗方案和预后判断。
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| 关 键 词： | 陷阱受体3 Fas/FasL系统 消化系肿瘤 进展 |
| 文章编号： | 1672-2019（2007）01-0103-02 |
| 收稿时间： | 2006-08-11 |
| 修稿时间： | 2006-08-11 |
Research progress of the relationship between Decoy receptor3 (DcR3) and Fas/FasL system and digestive system carcinoma |
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| CHEN Zhang-ming,ZHANG Yang-de,REN Si-lan,PAN Yi-feng. Research progress of the relationship between Decoy receptor3 (DcR3) and Fas/FasL system and digestive system carcinoma[J]. China Medical Engineering, 2007, 15(1): 103-104,106 |
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| Authors: | CHEN Zhang-ming ZHANG Yang-de REN Si-lan PAN Yi-feng |
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| Abstract: | Decoy receptor3 (DcR3) is a new member of TNF superfamily, and the expression of DcR3 increased in many tumor especially digestive system carcinoma, which may combined with FasL to interfere Fas/FasL system, then to induce tumor. The research of the relationship between DcR3 and Fas/FasL system and digestive system carcinoma helps to clarify the mechanism of digestive system carcinoma, and it gives a new way to resolve the tumor and to clinical treatment and prognosis. |
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| Keywords: | decoy receptor3 Fas/FasL system digestive system carcinoma progress |
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