| 佛山地区淋球菌流行株对抗生素敏感性测定 |
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| 引用本文： | 李燕娃,潘洪亮,吴兴中.佛山地区淋球菌流行株对抗生素敏感性测定[J].热带医学杂志,2009,9(7). |
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| 作者姓名： | 李燕娃 潘洪亮 吴兴中 |
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| 作者单位： | 1. 广东省佛山市皮肤病防治所,佛山,528000
2. 广东省皮肤性病防治中心,广州,510500 |
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| 摘 要： | 目的了解佛山地区2007年分离的淋球菌流行株对青霉素、四环素、大观霉素、头孢曲松和环丙沙星的耐药性及产β-内酰胺酶淋球菌(PPNG)和四环素高度耐药淋球菌(TRNG)的流行状况。方法采用琼脂稀释法测定最小抑菌浓度(MIC),纸片酸度法检测β-内酰胺酶。结果98株淋球菌检出PPNG34株(34.7%),TRNG63株(64.3%)。青霉素、环丙沙星和四环素的耐药率分别为96.9%、96.9%和94.9%,未发现大观霉素及头孢曲松耐药株。青霉素﹑四环素和环丙沙星的MIC50及MIC90均已超过耐药标准,尤以青霉素为甚,其MIC50及MIC90均超过耐药标准的8倍和32倍。结论大观霉素及头孢曲松是治疗淋病的首选药物。
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| 关 键 词： | 淋球菌 抗菌药物 耐药性 |
Detection of the Antibiotics Susceptibe Epidemic Strains of Neisseria gonorrhoeae in Foshan City |
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| LI Yan-wa,PAN Hong-liang,WU Xing-zhong.Detection of the Antibiotics Susceptibe Epidemic Strains of Neisseria gonorrhoeae in Foshan City[J].Journal Of Tropical Medicine,2009,9(7). |
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| Authors: | LI Yan-wa PAN Hong-liang WU Xing-zhong |
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| Institution: | Foshan Municipal Institute of Dermatology and Venerology;Foshan 528000;China |
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| Abstract: | Objective To investigate the antibiotics susceptibility of Neisseria gonorrhoeae isolated in Foshan city in 2007.Methods Agar dilution method was used to determine the minimum inhibitory concentrations(MICs) of the isolates to penicillin G, tetracycline, ciprofloxacin, ceftriaxone and spectinomycin.Penicillinase produced by N.gonorrhoeae(PPNG) was analysed by the paper acidometric method.Results 98 N.gonorrhoeae isolates were identified, in which 34.7% were PPNG and 64.3% were TRNG.The percentage of drug re... |
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| Keywords: | Neisseria gonorrhoeae antibacterial agent drug resistance |
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