急性心肌梗死发病与入院时C-反应蛋白水平的关系

目的　为了明确入院时C-反应蛋白(CRP)水平与急性心肌梗死(AMI)发病间的关系。方法　96例AMI患者根据入院6小时内测得的CRP水平将其分为3组,C组53例(CRP0.002～0.006g/L);L组25例(CRP＜0.026g/L);H组18例(CRP≥0.026g/L)。所有入选患者入院时立即给予冠状动脉造影术,CRP测定采用散射速率比浊法。结果　入院时CRP升高较CRP不高的患者在AMI发病前不稳定型心绞痛发病率高(P＜0.05),且在AMI发病时身体活动处于较低水平(P＜0.001),与梗死范围及受累血管数目无关。结论　AMI发病受到梗死前炎症活动的影响。

Relation betweenC-reactive protein levels on admission and pattern of acute myocardial infarction onset

Objective　To examine the relation between CRP levels on admission and the onset pattern of AMI to estimate the contribution of inflammation to the pathogenesis of AMI.Methods　Total 96 patients with AMI according to their CRP levels within the first 6 hours after the onset of AMI are divided into three groups,group C,n＝53(CRP 0.002～0.00 6 g/L);group L,n＝25(CRP＜0.026 g/L);group H,n＝18(CRP≥0.026 g/L).Coronary angi ography was performed immediately after admission in all patients.CRP levels were measured by scatter rate turbidity comparison.Results　Patients with elevated CRP levels were more likely to have had ahistory of unsta ble angina and symptom onset at lower level of physical activity than those with out elevated CRP levels (P＜0.05,P＜0.001).Conclusion　The pathogenesis of AMI may be influenced by preexisting inflammatory activity.