Meloxicam and selective COX-2 inhibitors in the management of pain in the palliative care population |
| |
Authors: | Smith Howard S Baird Whitney |
| |
Affiliation: | UPMC Presbyterian Pain Medicine, Department of Anesthesiology, Pittsburgh, Pennsylvania, USA. |
| |
Abstract: | This paper discusses the treatment of pain in the palliative care patient, specifically the use of meloxicam and recent advances in agents with cyclooxygenase-2 (COX-2) selectivity. Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that preferentially inhibits COX-2 more than cyclooxygenase-1 (COX-1), especially at low doses, thereby offering advantages over traditional nonselective NSAIDs. New COX-2 selective agents are discussed, including valdecoxib, parecoxib, etoricoxib, and COX-189. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|