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Death Receptor 5 Internalization Is Required for Lysosomal Permeabilization by TRAIL in Malignant Liver Cell Lines |
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| Authors: | Yuko Akazawa Justin L. Mott Steven F. Bronk Nathan W. Werneburg Alisan Kahraman Maria Eugenia Guicciardi Xue Wei Meng Shigeru Kohno Vijay H. Shah Scott H. Kaufmann Mark A. McNiven Gregory J. Gores |
| Affiliation: | ?Miles and Shirley Fiterman Center for Digestive Diseases, Division of Gastroenterology and Hepatology, College of Medicine, Mayo Clinic, Rochester, Minnesota;§Division of Oncology Research, College of Medicine, Mayo Clinic, Rochester, Minnesota;∥Department of Biochemistry and Molecular Biology, College of Medicine, Mayo Clinic, Rochester, Minnesota;‡Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan |
| Abstract: | |
| Keywords: | Abbreviations used in this paper: DAPI, 4&prime ,6-diamidino-2-phenylindole DR, death receptor EGFP, enhanced green fluorescent protein shRNA, short hairpin RNA siRNA, small interfering RNA TIRF, total internal reflection microscopy TRAIL, tumor necrosis factor&ndash related apoptosis-inducing ligand |
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