Heroin-induced myopathy in rat skeletal muscle |
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| Authors: | J. Pena C. Aranda E. Luque R. Vaamonde |
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| Affiliation: | (1) Department of Cell Biology, Faculty of Medicine, University of Córdoba, E-14071 Córdoba, Spain;(2) Department of Morphological Sciences (Histology and Embriology), Faculty of Medicine, University of Córdoba, E-14071 Córdoba, Spain;(3) Division of Anatomic Pathology, Reína Sofía Hospital, Córdoba, Spain |
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| Abstract: | Summary The effects of heroin on rat skeletal muscle was studied. Heroin was injected intraperitoneally, and the soleus and tibial anterior muscles were studied using histological and histochemical techniques. Degenerative and regenerative changes were detected, the latter proving more significant. The soleus was the only muscle affected, the anterior tibial showing no sign of damage. The heroin myopathy model may be valuable in studying muscle fibre necrosis and regeneration. |
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| Keywords: | Skeletal muscle Heroin Myopathy |
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