促甲状腺素（TSH）与绝经后甲状腺功能正常的 2 型糖尿病女性患者骨密度的相关性研究

目的探讨促甲状腺素(TSH)与停经1年以上的绝经后甲状腺功能正常的2型糖尿病女性患者骨密度的相关性。方法选取307例绝经后甲功正常2型糖尿病女性患者,根据TSH值的水平分层,分为A、B组,收集并比较两组间一般资料、骨密度的差异。结果 TSH与腰椎骨密度呈正相关,与股骨颈、Ward三角、股骨大转子、股骨干、股骨全部无明显相关关系。结论在甲功正常绝经后2型糖尿病女性患者中,维持TSH在正常高值水平,有利于预防骨质疏松的发生。

A study on the correlation between thyroid stimulating hormone and bone mineral density in postmenopausal patients with normal thyroid function and type 2 diabetes

Objective To investigate the correlation between thyroid stimulating hormone (TSH) and bone mineral density (BMD) in postmenopausal women with normal thyroid function and type 2 diabetes. Methods Three hundred and seven postmenopausal patients with type 2 diabetes were selected. According to the TSH levels, they were divided into group A (low TSH group) and group B (high TSH group). The general clinical data and BMD of the two groups were collected and compared. Results There was a positive correlation between TSH and BMD of the lumbar vertebrae. There was no significant correlation between TSH and BMD of the femoral neck, Wards triangle, femoral greater trochanter, femoral shaft, and the total femur. Conclusion In postmenopausal patients with type 2 diabetes and normal thyroid function, it is beneficial to keep TSH in a high level within the normal range for the prevention from osteoporosis.