Synthesis of N,N‐diethyl‐4‐[phenyl‐(piperidin‐4‐ylidene)methyl]‐[carboxy‐14C]benzamide,a potent δ opioid receptor agonist |
| |
Abstract: | The synthesis of carbon‐14 labelled N,N‐diethyl‐4‐phenyl‐(piperidin‐4‐ylidene)methyl]‐benzamide is described. The radioisotope is introduced via an aryllithium reaction with 14CO2 to form the labelled acid, which is subsequently transformed into the amide. Copyright © 2002 John Wiley & Sons, Ltd. |
| |
Keywords: | δ agonist benzamide carbon‐14 aryllithium |
|
|