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Iridium‐mediated β‐deuteration of enones |
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| Abstract: | Exposure of captodative enone systems to deuterium in the presence of Crabtree's catalyst ( 1 ) results in deuteration at the vinylic site β‐ to the ketone carbonyl, as well as at any accessible ortho‐position. β‐exchange is also observed during the reduction of ethyl cinnamate ( 3 ) catalyzed by 1 . Copyright © 2003 John Wiley & Sons, Ltd. |
| Keywords: | iridium complexes isotope exchange vinylic deuteration ortho‐deuteration [2H]‐SR46349 |