| 丙氧氨酚与酮咯酸治疗癌痛的比较 |
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| 引用本文： | 黄新思. 丙氧氨酚与酮咯酸治疗癌痛的比较[J]. 中国新药与临床杂志, 1995, 0(1) |
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| 作者姓名： | 黄新思 |
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| 作者单位： | 江苏省肿瘤医院内科 |
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| 摘 要： | 晚期肿瘤疼痛病人３１例（男性１７例，女性１４例，年龄５０±５１４ａ），用丙氧氨酚２片，ｐｏ，ｔｉｄ，共７ｄ。相似病人３０例（男性１６例，女性１４例，年龄５１±１３ａ），用酮咯酸１０ｍｇ，ｐｏ，ｑｉｄ，共７ｄ。结果：疼痛强度（标尺法）２组均有降低；显效时间前组（丙氧氨酚）快于后组（酮咯酸）；药效维持时间后组长于前组；不良反应前组嗜睡多于后组，而胃肠道不适少于后组。
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| 关 键 词： | 右丙氧酚；酮咯酸；疼痛；丙氧氨酚；对乙酰氨基酚 |
Propoxyacetamol vs ketorolac in treating malignant pain |
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| HUANG Xin-En. Propoxyacetamol vs ketorolac in treating malignant pain[J]. Chinese Journal of New Drugs and Clinical Remedies, 1995, 0(1) |
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| Authors: | HUANG Xin-En |
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| Abstract: | A control trial of propoxyacetamol(31 patients,M 17,F 14;age 50±s 14 a,dose 2 tablets.tid for7d)vs ketorolac(30patients,M 16,F 14;age 51±13 a,dose 10mg,po,qid for 7d)in treating advanced malignant pain was reported.At the end of therapy,both drugs showed good pain-relief efficacies with pain intensity significantly decreased.The pain-relief appeared earlier in pro propoxyacetamol group than in ketorolac group but lasted longer in ketorolac group(P<0.05).As to the adverse reactions,somolence was more in propoxyacetamol group than that in ketorolac group.but gastrointestinal discomfort was less than ketorolac group(P<0.05). |
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| Keywords: | propoxyphene ketorolac pain propoxyacetamol paracetamol |
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