Switching the therapy from etanercept to infliximab in a child with rheumatoid factor positive polyarticular juvenile idiopathic arthritis |
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Authors: | Yasuhito Nerome Hiroyuki Imanaka Yukiko Nonaka Syuji Takei |
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Institution: | (1) Department of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan |
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Abstract: | Tumor necrosis factor α (TNFα)-blocking agents have been used increasingly in the treatment of severe refractory juvenile
idiopathic arthritis (JIA). However, some patients have been forced to discontinue these agents because of the lack of efficacy
or adverse events. In these situations, cases of switching from one TNF-blocking agent to another are reported in rheumatoid
arthritis, but there are few cases in JIA. This report documents the case of a patient with JIA who improved following a switch
from etanercept to infliximab. |
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Keywords: | Etanercept Infliximab Juvenile idiopathic arthritis |
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