| 唐古特大黄有效成分与色度相关性分析 |
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| 引用本文： | 王君梅,郭玫,王志旺,曹强,郭亚菲,甘玉伟,康生福.唐古特大黄有效成分与色度相关性分析[J].中国中医药信息杂志,2022(3):105-109. |
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| 作者姓名： | 王君梅 郭玫 王志旺 曹强 郭亚菲 甘玉伟 康生福 |
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| 作者单位： | 甘肃中医药大学;甘肃省高校中（藏）药化学与质量研究省级重点实验室;甘肃省中药药理与毒理学重点实验室;甘南州科技交流开发中心;甘南百草生物科技开发有限公司 |
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| 基金项目： | 甘肃省中央引导地方科技发展专项-地方科技创新项目(2019年);甘肃省教育厅“双一流”科研重点项目(GSSYLXM-05);甘肃中医药大学研究生创新基金(2021CX45)。 |
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| 摘 要： | 目的 考察唐古特大黄主要药效成分与色度的相关性,建立快速评价唐古特大黄质量的色度分析方法.方法 采用HPLC测定唐古特大黄有效成分的含量,采用SPSS21.0软件进行主成分分析;测定唐古特大黄色度值L*、a*、b*、E*ab,分析其与有效成分的相关性.结果 主成分分析结果显示,总蒽醌、游离蒽醌、番泻苷A、番泻苷B的累计...
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| 关 键 词： | 唐古特大黄 主成分分析 色度分析 质量评价 |
Correlation Analysis of Effective Components and Chromaticity of Rheum tanguticum Maxim. |
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| WANG Junmei,GUO Mei,WANG Zhiwang,CAO Qiang,GUO Yafei,GAN Yuwei,KANG Shengfu.Correlation Analysis of Effective Components and Chromaticity of Rheum tanguticum Maxim.[J].Chinese Journal of Information on Traditional Chinese Medicine,2022(3):105-109. |
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| Authors: | WANG Junmei GUO Mei WANG Zhiwang CAO Qiang GUO Yafei GAN Yuwei KANG Shengfu |
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| Institution: | (Gansu University of Chinese Medicine,Lanzhou 730000,China;Provincial Key Laboratory of Chinese(Tibetan)Pharmaceutical Chemistry and Quality Research in Universities of Gansu Province,Lanzhou 730000,China;Key Laboratory of Pharmacology and Toxicology of Traditional Chinese Medicine of Gansu Province,Lanzhou 730000,China;Gannan Science and Technology Exchange and Development Center,Gannan 747000,China;Gannan Baicao Biotechnology Development Co.,LTD.,Gannan 747000,China) |
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| Abstract: | Objective To investigate the correlation between the main pharmacodynamic components and chromaticity of Rheum tanguticum Maxim.;To establish a rapid chromaticity analysis method for evaluating the external quality of Rheum tanguticum Maxim.Methods The contents of active components in Rheum tanguticum Maxim.were determined by HPLC,and the principal components were analyzed by SPSS 21.0;the chromaticity values L*,a*,b*,and E*ab were determined,and the correlation between the values and the effective components of Rheum tanguticum Maxim.was analyzed.Results The results of principal component analysis showed that the cumulative contribution rate of total anthraquinones,free anthraquinones,sennoside A,and sennoside B reached 47.148%,which were the main chemical components in Rheum tanguticum Maxim.;the correlation between the chromaticity value and the active components showed that the values of b*and E*ab were significantly correlated with the contents of total anthraquinones,sennoside B,and sennoside A.Conclusion Chromaticity analysis can quickly evaluate the external quality of Rheum tanguticum Maxim..The internal and external quality control methods can be more objective,effective and rapid to evaluate the quality of Rheum tanguticum Maxim.. |
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| Keywords: | Rheum tanguticum Maxim principal component analysis chromaticity analysis quality evaluation |
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