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磺胺嘧啶银膜剂的制备及质量控制
引用本文:吴继禹,王志强,黄学荪.磺胺嘧啶银膜剂的制备及质量控制[J].中国药房,2005,16(6):432-433.
作者姓名:吴继禹  王志强  黄学荪
作者单位:温州医学院附属第一医院药剂科,温州市,325000
摘    要:目的 :研制磺胺嘧啶银膜剂并建立其质量控制方法。方法 :以聚乙烯醇为主要辅料制备膜剂 ,用永停滴定法测定主药含量 ,并留样观察其稳定性。结果 :样品中磺胺嘧啶银含量为98. 9 %~100 .7 % ,平均加样回收率为100. 6 % ,RSD=0 .69 % (n=6)。结论 :所制膜剂质量稳定 ,含量准确 ;制备工艺简单 ,检测方法快捷。

关 键 词:磺胺嘧啶银  膜剂  制备
文章编号:1001-0408(2005)06-0432-02
修稿时间:2004年7月5日

Preparation of Sulfadiazine Silver Film and Its Quality Control
WU Jiyu,WANG Zhiqiang,HUANG Xuesun.Preparation of Sulfadiazine Silver Film and Its Quality Control[J].China Pharmacy,2005,16(6):432-433.
Authors:WU Jiyu  WANG Zhiqiang  HUANG Xuesun
Abstract:OBJECTIVE:To prepare sulfadiazine silver film and establish a way for its quality control.METHODS:Polyvinyl alcohol was used as the main excipients for the preparation of film;the dead-stop titration was used to determine the content of sulfadiazine silver;the stability of the film sample was observed.RESULTS:The content of sulfadiazine silver was 98.9%~100.7%,the average recovery rate was 100.6%,RSD=0.69%(n=6).CONCLUSION:The prepared sulfadiazine silver film is stable in quality,accurate in content,simple in preparation and the testing method is fast.
Keywords:Sulfadiazine silver  Film  Preparation
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