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抗脂肪肝中剂对大鼠高脂血症防治的实验研究
引用本文:黄顺玲,谢晃君,文体端,常伟宏,吴小宇,周建新,蒋芳清,王敏.抗脂肪肝中剂对大鼠高脂血症防治的实验研究[J].临床消化病杂志,2001,13(6):262-263.
作者姓名:黄顺玲  谢晃君  文体端  常伟宏  吴小宇  周建新  蒋芳清  王敏
作者单位:湖南省长沙市肝病研究所,
基金项目:湖南省科委资助攻关课题(1013-61)
摘    要:目的:探讨抗脂肪肝冲剂对高脂血症大鼠脂质代谢的影响,寻求防治高脂血症的有效药物。方法:采用高脂饮食喂养大鼠,形成高脂血症模型,饲以抗脂肪肝冲剂,观察大鼠血清总胆固醇(TC)及甘油三酯(TG)的含量,结果:抗脂肪肝冲剂能显著降低高脂血症大鼠血清中TC含量(与模型对照组比较P<0.01)及TG含量(大、中、小剂量组与模型对照组比较P<0.01,P<0.05,P<0.05)。结论:抗脂肪肝冲剂能够降低高脂血症大鼠TC、TG的含量,具有防治高脂血症的作用。

关 键 词:抗脂肪肝冲剂  高脂血症  大鼠  防治
修稿时间:2001年6月10日

Laboratory Research About the Anti-Fatty Liver Mixture in Preventing and Treating the Hyperlipidemia of Rats
Huang Shun-lin,Xie Huang-jun,Wen Ti-duan,et alChangsha Municipal Hepatic Diseases Institute,Changsha.Laboratory Research About the Anti-Fatty Liver Mixture in Preventing and Treating the Hyperlipidemia of Rats[J].Chinese Journal of Clinical Gastroenterology,2001,13(6):262-263.
Authors:Huang Shun-lin  Xie Huang-jun  Wen Ti-duan  Changsha Municipal Hepatic Diseases Institute  Changsha
Institution:Huang Shun-lin,Xie Huang-jun,Wen Ti-duan,et alChangsha Municipal Hepatic Diseases Institute,Changsha 410011
Abstract:Purpose: To investigate the effect of the anti-fatty liver mixture on lipometabolism of rats, find an efficient medicine in preventing and treating hyperlipidemia. Methods: Using the rat models which were fed by high fat diet, then the rats' serum content of TC and TG were investigated. Results: The serum content of TC in these rats was declined by the anti-fatty liver mixture compared with the contrast models( P < 0.01). The serum content of TG was declined too in the large dosage group( P < 0.01), and in the middle and small dosage groups(P<0.05). Conclusion: The anti fatty liver mixture can significantly decline the serum content of TC and TG in the rats with hyperlipidemia. It is an effective medicine in preventing and treating the hyperlipidemia.
Keywords:Anti fatty liver mixture  Hyperlipidemia  Rat
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