| 灯盏乙素在抑制冠脉搭桥术后静脉桥再狭窄中的应用 |
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| 作者姓名： | 张浒 彭安睿 钟佳冀 黄波 白鹏 |
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| 作者单位： | 1.昆明医科大学第一附属医院心脏大血管外科 |
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| 基金项目： | 云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目[2017FE467（-029）]；云南省教育厅科学研究基金资助项目（2021J0242） |
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| 摘 要： | 目的 通过临床对照研究,观察灯盏乙素对冠状搭桥术后静脉桥再狭窄的作用.方法 根据入选和排除标准纳入冠脉搭桥术后患者64例,随机平均分2组(n=32),对照组患者术后口服常规药物,治疗组除常规药物外,增加灯盏花素片,术后3个月、6个月多层计算机断层血管造影(MSCTA)来检测静脉桥,评估静脉桥再狭窄,2组对比分析.结果 ...
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| 关 键 词： | 冠脉搭桥术 静脉桥 再狭窄 灯盏乙素 抑制 |
| 收稿时间： | 2021-12-17 |
The Application of Breviscapine on Graft Restenosis in Coronary Artery Bypass Grafting |
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| Authors: | ZHANG Hu PENG Anrui ZHONG Jiaji HUANG Bo BAI Peng |
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| Institution: | 1.Dept. of Cardiovascular Surgery2.Operating Room3.Dept. of Neurosurgery，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China |
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| Abstract: | Objective To explore the protective effect of breviscapine on graft vein grafting in the patients who underwent Coronary Artery Bypass Graft （CABG）. Methods According to the inclusion criteria and exclusion criteria, 64 patients entered the study and were randomly divided into two groups （n = 32）. Group A was the control group, in which patients took oral routine drugs including aspirin, clopidogrel and atorvastatin; Group B was the treatment group, in which patients took oral routine drugs + breviscapine. The rate of graft stenosis was examined by Multi-slics Computed Tomography Angiography （MSCTA） 3 months and 6 months after CABG. Results The rate of graft stenosis in the treatment group was significantly lower than that in the control group 3 and 6 months after CABG （P < 0.05）. Conclusion Breviscapine has a protective effect on graft veins in patients who underwent CABG. |
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