| 癫痫患者脑脊液细胞因子含量变化及其意义 |
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| 引用本文： | 许文华,余峰,任佰玲,汪银洲. 癫痫患者脑脊液细胞因子含量变化及其意义[J]. 中国临床保健杂志, 2004, 7(3): 190-191 |
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| 作者姓名： | 许文华 余峰 任佰玲 汪银洲 |
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| 作者单位： | 安徽省立医院神经内科,合肥,230001;安徽省立医院神经内科,合肥,230001;安徽省立医院神经内科,合肥,230001;安徽省立医院神经内科,合肥,230001 |
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| 摘 要： | 目的 探讨癫痫患者脑脊液中细胞因子含量变化及其意义。方法 应用放射免疫法对 4 3例癫痫患者脑脊液中IL 2、IL 6、IL 8和TNF α含量进行了检测。结果 癫痫患者脑脊液中IL 2、IL 6、IL 8和TNF α含量明显高于对照组 (P <0 0 0 1～ 0 0 5 )。相关分析发现脑脊液中细胞因子含量与癫痫发作频率呈正相关。结论 细胞因子可能参与了癫痫患者的发病
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| 关 键 词： | 癫痫 细胞因子 脑脊液 |
| 文章编号： | 1672-6790(2004)03-0190-02 |
| 修稿时间： | 2004-03-28 |
Change of cytokines levels in cerebrospinal fluid of epileptic patients and its significance |
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| XU Wenhua,YU Feng,RENG Bailing,et al.. Change of cytokines levels in cerebrospinal fluid of epileptic patients and its significance[J]. Chinese Journal of Clinical Healthcare, 2004, 7(3): 190-191 |
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| Authors: | XU Wenhua YU Feng RENG Bailing et al. |
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| Abstract: | Objective To probe into the change of cytokines levels in cerebrospinal fluid of epileptic patients and its significance.Methods The cerebrospinal fluid levels of IL-2,IL-6,IL-8 and TNF-α in 43 epileptic patients and 32 controls were measured by radioimmunoassay.Results The mean IL-2,IL-6,IL-8 and TNF-α levels in epileptic patients were markedly higher than those of the controls(P<0.001～0.05).There was positive correlation between cytokines and epileptic frequency.Conclusion The results indicates that cytokines may play a role in the pathogenesis of epileptic patients. |
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| Keywords: | Epilesy Cytokine Cerebrospinal fluid |
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