液基薄层细胞学检测的病理诊断价值评价分析

目的:评价液基薄层细胞学技术(Thinrepcytologic test,TCT)检查的病理诊断价值。方法:对2007年1月～2009年11月1009例TCT阳性病例与宫颈病理组织学检查(活检)结果进行回顾性对比分析。结果:TCT提示不同感染程度的慢性宫颈炎患者的病理诊断检出率分别为98.86%(轻度)、92.22%(中度)和92.55%(重度),ASC-US和ASC-H与慢性宫颈炎的符合率达到94.17%,LSIL与CIN1和CIN2符合率达到88.89%,HSIL和CIN3符合率达到87.50%,宫颈癌符合率达到100.0%。结论:对宫颈病变患者进行TCT联合阴道镜下宫颈活检可早期发现宫颈癌和癌前病变,有助于宫颈疾病的进一步诊疗。

Evaluation and analysis on pathological diagnostic value of TCT

Objective:To evaluate the pathological diagnostic value of thinprep cytologic test (TCT).Methods:The results of TCT and corresponding cervical pathological diagnosis (biopsy) among 1 009 cases from January 2007 to November 2009 were compared.Results:Among the cases diagnosed as chronic cervicitis at different levels by TCT, the detection rate of pathological diagnosis were 98.86% (mild), 92.22% (middle) and 92.55% (severe), respectively, the coincidence between ASC-US, ASC-H and chronic cervicitis were 94.17%, the coincidence between LSIL, CIN 1 and CIN 2 was 88.89%, the coincidence between HSIL and CIN 3 was 87.50%, the coincidence of cervical cancer was 100.0%. Conclusion:TCT combined with cervical biopsy under colposcope can find cervical cancer and precancerous lesions of uterine cervix early, which contributes to further diagnosis and treatment of cervical diseases.