| 乙肝后肝硬化患者血清1,25(OH)2D3检测及其临床意义 |
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| 引用本文： | 陈自平,刘倩,王文奇,王义国,闫明先. 乙肝后肝硬化患者血清1,25(OH)2D3检测及其临床意义[J]. 临床肝胆病杂志, 1999, 15(1): 57-59 |
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| 作者姓名： | 陈自平 刘倩 王文奇 王义国 闫明先 |
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| 作者单位： | 250014,山东省千佛山医院消化内科 |
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| 摘 要： | 采用竞争性放射受体法测定３２例乙肝后肝硬化患者血清１Ｍ２５（ＯＨ）２Ｄ３水平，并与３２例性乙型肝炎、３１例健康者对照。发现：肝硬化组血清１，２５（ＯＨ）２Ｄ３水平较肝炎组和对照组明显下降（Ｐ〈０．０１，Ｐ〈０．００１），且与血清骨钙素、尺桡密度呈正相关（Ｐ〈０．０１，Ｐ〈０．０５）。提示：测定乙肝后肝硬化患者血清１，２５（ＯＨ）２Ｄ３水平有利于肝性骨病的早期发现。
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| 关 键 词： | 肝炎后肝硬化 1 25(OH)2D3 骨钙素 骨密度 |
| 修稿时间： | 1997-10-15 |
Detection and Clinical Significance of Serum 1,25 (OH)2D3 in Posthepatitic Cirrhosis |
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| ChenZiping,LiuQian,WangWenqi,etalShandongProvinceQianfoshanHospital. Detection and Clinical Significance of Serum 1,25 (OH)2D3 in Posthepatitic Cirrhosis[J]. Chinese Journal of Clinical Hepatology, 1999, 15(1): 57-59 |
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| Authors: | ChenZiping LiuQian WangWenqi etalShandongProvinceQianfoshanHospital |
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| Affiliation: | ChenZiping,LiuQian,WangWenqi,etalShandongProvinceQianfoshanHospital250014 |
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| Abstract: | Inordertostudytherelationshipbetweenserum1,25(OH)2D3andhepaticbonedisease(HBD),levelsofserum1,25(OH)2D3weredetectedbycompeitiveradioreceptorassayin32livercirrhosis(LC),32chronichepatitisB(CHB)and31healthycontrolsTheresultsshowedthatlevelsofserum1,25(OH)2D3werelowermoresignificantlyinLCandCHBthanthecontrols( P<0001, P <001)respectively,andthelevelofLCdecreasedevenmorethanCHBgroup( P <001)Postivecorrelantionbetweenthelevelofserum1,25(OH)2D3andosteocalcinorbonemineraldensitywerefound(r=04761,WTBXP <001;r=04294, P <005)Itissuggestedthat1,25(OH)2D3inLCisausefulindexformornitoringHBDontheearlystage |
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| Keywords: | PosthepatiticCirrhosis 1 25(OH)2D3OsteocalcinBoneMineralDensity |
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