降钙素原检测在肺炎患者中的应用

目的:观察降钙素原检测在肺炎患者中的应用效果。方法:选择200例肺炎患者,随机分为两组:降钙素原组和对照组。降钙素原组根据血清降钙素原水平指导是否使用抗生素,对照组由主管医生参考抗生素使用指南判断是否使用抗生素。记录两组治疗有效的患者例数、死亡患者例数、使用抗生素的患者例数、住院时间、住院费用。结果:两组患者的有效率和死亡率差异无统计学意义(P>0.05)。但降钙素原组使用抗生素的患者明显少于对照组的患者(P<0.05)。两组患者的住院时间比较,差异无统计学意义(P>0.05)。降钙素原组患者的住院费用少于对照组(P<0.05)。结论:降钙素原指导抗生素使用,可降低抗生素使用率,减少患者医疗费用。

Application of procalcitonin in the patients underwent pneumonia

Objective To observe the application effect of procalcitonin in the patients underwent pneumonia. Method Two hundred patients underwent pneumonia were divided into two groups ： proealeitonin group and control group. In the proealcitonin group, antibiotics were used according to serum procaleitonin concentration. In the control group, antibiotics were used according to antibiotic use guide. The effective rate, mortality, antibiotic use rate,hospital stays,hospitalization expenses in both groups were recorded. Results The effective rate and mortality were not siguifieantly different between two groups （ P 〉 0. 05 ）. The antibiotic use rate in the procalcitonin group was lower than it in the control group（ P 〈0. 05 ）. The hospital stays were not significantly different between two groups（ P 〉 0. 05 ）. The hospitaliza- tion expenses in the proealcitonin group were less than those in the control group（ P 〈 0. 05 ）. Coneluslon Using antibiotics according to serum proealcitonin concentration can decrease the antibiotic use rate and the hospitalization expenses.