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Investigating the Signal Transduction Pathways Underlying Remote Ischemic Conditioning in the Porcine Heart
Authors:D. J. Hausenloy  E. K. Iliodromitis  I. Andreadou  A. Papalois  G. Gritsopoulos  M. Anastasiou-Nana  D. T. Kremastinos  D. M. Yellon
Affiliation:(1) The Hatter Cardiovascular Institute, University College London Hospital & Medical School, London, UK;(2) 2nd University Department of Cardiology, Attikon General Hospital, Medical School, University of Athens, Athens, Greece;(3) Department of Pharmaceutical Chemistry, School of Pharmacy, University of Athens, Athens, Greece;(4) The Hatter Cardiovascular Institute, University College London Hospital and Medical School, 67 Chenies Mews, London, WC1E 6HX, UK;
Abstract:

Background  

The mechanism underlying remote ischemic conditioning (RIC) remains unclear. We investigated whether RIC protects the heart through the activation of the adenosine receptor and the PI3K-Akt pathway at the onset of myocardial reperfusion.
Keywords:
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