接骨丹对大鼠骨缺损愈合疗效的影像学研究

目的:探讨接骨丹对骨缺损愈合及骨形成的影响。方法:采用开放性骨折模型制作方法制作大鼠骨缺损模型,通过拍摄胫骨X光片,并根据骨折肢X片评分标准,对各组大鼠不同时间段骨折肢进行相应评分,考察接骨丹对骨折愈合及骨形成的影响。结果:给药组较空白组骨缺损部位骨痂生成良好、骨缺损明显减小、骨折肢X线片评分明显高于空白对照组(P0.05)。结论:接骨丹对骨缺损愈合及骨形成有促进作用。

Imaging Study on Curative Effects ofJieGuPills in Healing the Rats with Bone Defect

Objective: To explore the influence ofJieGupills on the healing of bone defect and bone forma-tion. Methods: Rat model with bone defect was prepared by adopting open bone fracture model establishment method, the fracture limb of the rats in different groups were scored at different times by filming tibial X-ray accord-ing to fractured limb X-ray scaling standard, and the influence ofJieGupills on the healing of bone fracture and bone formation was discussed. Results: Callus formation grew well, and bone defects reduced obviously when the medication group was compared with the blank group, it was higher than blank control group in X-ray scales of frac-tured limbs obviously (P<0.05). Conclusion:JieGupills could promote the healing of bone defect and bone forma-tion.