中西药物联合治疗小儿毛细支气管炎55例

目的:分析中医药在改善小儿毛细支气管炎患者血清总Ig E水平中的作用。方法:将110例患儿随机分为观察组、对照组各55例,2组均应用西医常规治疗,观察组同时加服中药,1剂/d,水煎分服。观察2组治疗前后总Ig E水平、T细胞亚群的变化情况及症状体征缓解时间和临床疗效。结果:症状缓解时间观察组明显短于对照组(P0.05)。CD4~+、CD4~+/CD8~+及血清总Ig E水平2组治疗前后组内比较,差异均有统计学意义(P0.05);治疗后2组组间比较,差异均有统计学意义(P0.05)。总有效率观察组为94.55%,对照组为81.82%,2组比较差异有统计学意义(P0.05)。结论:在西药常规治疗的基础上采用中药治疗毛细血管炎患儿,临床疗效显著,且能够缩短病程,降低患者血清总Ig E水平,改善T细胞亚群状况。

Integrative Medicine for 55 Cases of Children with Capillary Bronchitis

Objective: To analyze the role of traditional Chinese medicine in improving the total serum IgE level in children with capillary bronchitis. Methods: All 110 cases were randomly divided into the observation group and the control group with 55 cases in each group. Both groups were treated with conventional western medicine while the observation group was treated with traditional Chinese medicine, one dose per day, and water decoction. The changes of total IgE levels, T cell subsets, the relief time of the symptoms and body signs, and clinical efficacy of bothgroups were observed before and after treatment. Results: Symptom relief time in the observation group was significantly shorter than that in the control group(P<0.05). When CD4+, CD4+/CD8+ and serum total IgE levels in the two groups before and after treatment were compared within groups, the differences were statistically significant(P<0.05). After treatment, the difference between the two groups was statistically significant(P<0.05). The total effective rate of the observation group was 94.55%, and the control group was 81.18%, the difference was statistically significant between both groups(P<0.05). Conclusion: On the basis of conventional treatment of Western medicine, traditional Chinese medicine treatment for capillary inflammation in children is effective, It can shorten the course of disease and reduce the total serum IgE level of patients as well as improve the status of T cell subsets.