基于文献的附子药理作用再评价

目的:对附子药理作用的确切性进行再评价。方法:通过查阅、整理、分析2015年以前公开发表的有关附子药理作用的研究文献,根据药物药理作用的评价原则和评定标准,对附子药理作用进行再评价,以明确其药理作用。结果:附子强心、抗心律失常、扩张血管、镇痛、抗炎、抗肿瘤作用明确,抗衰老、增强免疫等药理作用实验依据不足。结论:附子主要药理作用为强心、抗心律失常、扩张血管、镇痛、抗炎、抗肿瘤。

Re-evaluation of the Pharmacological Effects ofFuZiBased on Literature

Objective: To re-evaluate the certainty of the pharmacological effects ofFuZi(Aconitum carmichaeliDebx.). Methods: The pharmacological effects ofFuZiwas re-evaluated and determined based on the e-valuation principles and evaluation criteria of drug's pharmacological effects through inspecting, sorting and analyz-ing the research literature related to the pharmacological effects ofFuZipublished before 2015. Results:FuZipre-sented the obvious functions of strong heart, anti-arrhythmia, the dilation of blood vessels, analgesic, anti-inflamma-tory and anti-tumor. However, the experimental evidences of pharmacological effects such as anti-aging and strengthening immunity were insufficient. Conclusion: The main pharmacological effects ofFuZiare strong heart, anti-arrhythmia, the dilation of blood vessels, analgesic, anti-inflammatory and anti-tumor.