血脂与冠状动脉病变关系的探讨

目的　探讨血脂水平与冠状动脉病变的关系。方法　 2 2 8例进行过选择性冠状动脉造影的住院冠心病病人按冠状动脉狭窄程度积分为正常组、单支组、双支组、三支组四组。测定和比较血脂各项指标 TC、TG、HDL、L DL、apo A1 、apo B1 0 0 、L p(a)。结果　 L p(a)、HDL、apo A1 / apo B1 0 0 在各组之间存在着差异。L p(a)随着冠状动脉病变程度加重而增高 ,apo A1 / apo B1 0 0 随着冠状动脉病变程度加重而减少。 HDL与冠状动脉积分呈负相关 ,L p(a)与冠状动脉积分呈正相关。结论　 HDL和 L p(a)对预测冠状动脉病变有重要意义

A discussion of the relationship between serum lipids and the severity of the coronary arteriopathy

Objective To investigate the relationship between serum lipids and the severity of the coronary arteriopathy. Methods 228 patients with coronary artery disease that underwent a selective coronary angiography were divided into four groups according to the score of the severity of the coronary arteriopathy. Serum lipids(TC,TG,HDL,LDL,apoA 1,apoB 100,Lp(a)), in four groups were detected and compared. Results Lp(a) increased and apoA 1/apoB 100 decreased with the severity of the coronary arteriopathy . The severity of coronary arteriopathy was positively correlated with Lp(a) and negatively correlated with HDL. Conclusion HDL and Lp(a) may closely contribute to predict the severity of the coronary arteriopathy.