高血压孕妇妊娠期实施药物干预的效果观察

目的观察高血压孕妇在妊娠期实施早期药物干预的临床治疗效果。方法选取2007年1月至2012年1月在深圳市龙岗区平湖人民医院就诊的妊娠期高血压患者300例作为研究对象,其中2007年1月至2008年5月就诊的125例患者作为在妊娠期未进行药物干预的对照组,2008年6月至2012年1月就诊的175例患者作为在妊娠期进行早期药物干预的观察组,对比分析两组患者在产后出血、剖宫产、早产、胎儿窘迫及新生儿窒息方面的疗效情况。结果观察组患者的产后出血、剖宫产、早产、胎儿窘迫及新生儿窒息发生率与对照组相比明显降低,差异有统计学意义(P<0.05)。结论在临床实践中,对妊娠期高血压患者进行早期药物干预,能降低不良妊娠结局的发生率,从而改善妊娠结局,值得临床推广使用。

Observation on Effect of Drug Intervention on Gestational Hypertension

Objective To observe the curative effect of drug intervention on gestational hypertension.Methods From Jan.2007 to Jan.2012,300 gestational hypertension patients had been treated in Pinghu Hospital of Longgang District.Among these patients,125 cases treated with drug intervention were enrolled into this study as control group(from Jan.2007 to May 2008),while the other 175 cases treated with drug intervention were enrolled as observation group(from Jun.2008 to Jan.2012).The following parameters were compared and analyzed:postpartum hemorrhage,cesarean section,premature labor,fetal distress and neonatal asphyxia.Results Compared with the control group,the rates of postpartum hemorrhage,cesarean section,premature labor,fetal distress and neonatal asphyxia were significantly lower in observation group,the differences were statistically significant(P<0.05).Conclusion For patients with gestational hypertension,drug intervention is effective to reduce the rates of adverse pregnancy outcomes and worthy of clinically application.