| 寻常型银屑病、全身性红斑狼疮、胰岛素依赖性糖尿病患者GLO遗传多态性检测 |
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| 引用本文： | 吴雄文,赵修竹,孙曾拯,胡长发,张慧芳,项慧丽,祝希媛.寻常型银屑病、全身性红斑狼疮、胰岛素依赖性糖尿病患者GLO遗传多态性检测[J].华中科技大学学报(医学版),1989(3). |
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| 作者姓名： | 吴雄文 赵修竹 孙曾拯 胡长发 张慧芳 项慧丽 祝希媛 |
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| 作者单位： | 同济医科大学基础医学部病理生理学教研室
(吴雄文，赵修竹)，武汉市第一医院皮肤科
(孙曾拯，胡长发，张慧芳)，北京友谊医院内科
(项慧丽)，北京友谊医院内科(祝希媛) |
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| 摘 要： | 用琼脂糖-淀粉混合凝胶电泳技术及碘染色法对70份寻常型银屑病、74份全身性红斑狼疮、31份胰岛素依赖性糖尿病患者红细胞标本的乙二醛酶1(GLO)遗传多态性进行了检测,结果表明,上述3种疾病忠者GLO~1的频率分别为0.1214、0.0811、0.0484,与我们所测203例正常人红细胞GLO基因频率(GLO~1为0.1429)比较,差异均无显著意义。
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| 关 键 词： | 乙二醛酶 遗传多态性 寻常型银屑病 红斑狼疮 全身性 胰岛素依赖性糖尿病 |
Investigation on the Polymorphism of Glyoxalase 1(GLO) in Patients with Psoriasis Vulgaris, Systemic Lupus Erythematosus and Insulin-dependent Diabetes Mellitus |
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| Wu Xiongwen,Zhao Xiuzhu,Sun Zengzheng,Hu Changfa,Zhang Huifang,Xiang Huili,Zhu Xiyuan.Investigation on the Polymorphism of Glyoxalase 1(GLO) in Patients with Psoriasis Vulgaris, Systemic Lupus Erythematosus and Insulin-dependent Diabetes Mellitus[J].Journal of Huazhong University of Science and Technology(Health Sciences),1989(3). |
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| Authors: | Wu Xiongwen Zhao Xiuzhu Sun Zengzheng Hu Changfa Zhang Huifang Xiang Huili Zhu Xiyuan |
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| Institution: | Wu Xiongwen,Zhao Xiuzhu,Sun Zengzheng,Hu Changfa,Zhang Huifang,Xiang Huili,Zhu Xiyuan Department of Pathophysiology,Faculty of Basic Medical Sciences,TongjiMedical University,WuhanDepartment of Dermatology,Wuhan No.1 Hospital Department of Internal Medicine,Friendship Hospital,Beijing |
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| Abstract: | The GLO polymorphism of the patients with psoriasis vulgar is, systemic lupus erythematosus, insulin-dependent diabetes mellitus was determined. The GLO1 gene frequencies in the patients mentioned above are 0.1214, 0.0811, 0.0484 respectively, and show no statistically significant difference, as compared with those in the controls. |
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| Keywords: | glyoxalase 1 (GLO) polymorphism psoriasis vulgaris lupus ery thematosus systemic diabetes mellitus insulin-dependent |
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