多模态超声对桥本氏甲状腺炎背景下乳头状癌的诊断价值研究

目的：探讨甲状腺影像报告和数据系统（TI-RADS）常规超声分类、超声弹性成像(Ultrasonic elastography，UE)及超声造影（Ultrasonic Contrast，CU）多模态超声成像评分在桥本氏甲状腺炎（Hashimoto''s thyroiditis ，HT）背景下乳头状癌（papillary thyroid carcinoma ，PTC）的诊断价值。方法：选取经病理证实的HT合并甲状腺结节患者310例，共计结节339个，行2D、UE、CU，根据结果分为良性结节组和PTC组，对两组结节单一诊断方法及三者联合应用评分分布结果进行比较，使用ROC曲线对HT背景下PTC诊断效能进行分析并确定截点值。结果：良性结节组和PTC组单一诊断方法及三者联合应用评分分布比较差异具有统计学意义（P＜0.05）。ROC曲线下，多模态超声诊断PTC的AUC及诊断效能明显高于单一诊断方法（P＜0.05）。结论：多模态超声可提高HT背景下PTC的诊断效能，9.5分为良性结节及PTC的截点值。

The value of multimodal ultrasound in the diagnosis of papillary thyroidcarcinomain hashimoto

Objective: To explore the diagnostic value of thyroid image report and data system (TI-RADS) for papillary carcinoma in the background of Hashimoto''s thyroiditis (HT) by conventional ultrasound classification, ultrasound elastography(UE) and ultrasound contrast(CU) enhanced ultrasound multimodal ultrasound imaging score. Confirmed by pathological methods: select 310 patients with HT merged thyroid nodule, a total of 339 nodules, line of TI - RADS classification, UE and CU, according to the result can be divided into benign nodules and PTC group, on two groups of nodes in a single diagnosis method and the result of combined application of grade distribution comparison, using ROC curve under the background of hashimoto papillary carcinoma diagnosis efficiency analysis and determine the cut-off value. Results: There were statistically significant differences in the single diagnosis method and the combined application of the three methods between the benign nodular group and the PTC group (P < 0.05). Under ROC curve, the AUC and diagnostic efficiency of multimodal ultrasound for papillary carcinoma were significantly higher than that of single diagnosis method (P < 0.05). Conclusion: Multimodal ultrasonography can improve the diagnostic efficiency of PTC in the background of HT. 9.5 The cut-off point values of benign nodules and PTC.