| ^1H-MRS鉴别皮层区脑梗死与胶质瘤 |
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| 引用本文： | 王晋君,郭兴华,李建丁.^1H-MRS鉴别皮层区脑梗死与胶质瘤[J].中国CT和MRI杂志,2008,6(6):22-24. |
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| 作者姓名： | 王晋君 郭兴华 李建丁 |
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| 作者单位： | 山西省运城市中心医院影像科,044000 |
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| 摘 要： | 目的探讨质子波谱对皮层区脑梗死与胶质瘤的鉴别诊断价值。方法对9例皮层区胶质瘤及36例皮层区无特殊症状的脑梗死病例，采用点分辨选择法单体素（SVS—SE序列）采集，HMRS波谱信号，测量NAA、ChO、Cr峰下面积积分值，计算NAA／Cho，Cho／Cr两个比值，与健侧对应区，^1H—MRS相应数据作对照，做t检验，比较观察胶质瘤、脑梗死各指标的变化规律。结果与健侧相比，胶质瘤NAA、Cr下降（P〈0．01），Cho升高（P〈0．05），NAA／Cho下降（P〈0．01）。脑梗死病例急性期NAA、Cho、Cr、NAA／Cho与健侧相比均下降（P〈0．01），Lac峰较高。亚急性期以后各波均下降，慢性期各波全部消失在背景噪声波中。结论胶质瘤、脑梗死在^1HMRS上有各自特异性的波型变化，对鉴别诊断有一定意义。
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| 关 键 词： | 磁共振质子波谱 脑梗死 胶质瘤 |
The differential value of 1HMRS to cortical or subcortical cerebral infarction and glioma |
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| Authors: | WANG Jin-jun GUO Xing-hua LI Jian-ding |
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| Institution: | WANG Jin-jun,GUO Xing-hua,LI Jian-ding. Department of Medical Imaging,Shanxi YunCheng Central Hospital,YunCheng 044000,China. |
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| Abstract: | Objective To research the differential value of 1HMRS to cortical or subcortical cerebral infarction and glioma. Methods The 1HMRS of 9 cases of cortical and subcortical benign glioma and 36 cases of cortical and subcortical infarction were measured by PRESS and SVS-SE technique, and the integrals of NAA, Cho, Cr and the ratio of NAA/Cho were analyzed and compared with the opposite side 1HMRS by t- test. Results NAA, CR, NAA/Cho decreased(P < 0.01) but Cho increased(P < 0.05) in the patients of gliomas, while NAA, Cho,Cr and NAA/Cho decreased(P < 0.01) in acute cerebral infarction with a high Lac pike, and among the subacute period every wave decreased and all disappeared in chronic period of infarction. Conclusion Glioma and cerebral infarction have their own specific type of 1HMRS waves, which can be helpful to differential diagnosis. |
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| Keywords: | 1HMRS Cortical Infarction Glioma |
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