肾脏循环灌注对比超声声学特征

目的 探讨肾脏循环灌注对比超声声学显像特点。方法 对10条杂种犬注射全氟显声学造影剂进行肾脏对比超声检查。结果 肉眼下基础状态肾皮质至肾髓质、肾髓质由外至内呈渐进式显影。计算机视频分析示基础状态下皮质血管容积、血流速度、血流量均大于髓质,皮质和髓质血流速度的差异显著大于血管容积的差异。结论 肾脏对比超声检查为研究肾脏循环提供了一个窗口。

Expermential study of the characteristics of renal blood flow with contrast ultrasound

Objective To study the characteristics of renal blood flow with contrast ultrasound. Methods The examination of the renal ultrasonography was performed in 10 dogs after intravenous injection of Quanfuxian (a contrast agent consisting of C3F8 microbubbles). Results Contrast visualization appeared in the renal cortex and then in the outer to inner medulla at the baseline level after administration of the contrast agent. Notable differences in the values of microvascular volume (A, which was 120.3 in the corted vs 110.8 in the medulla, P>0.05), microcirculatory flow velocity (β, which was 1.39 in the corted vs 0.54 in the medulla, P<0.05), and microcirculatory flow rate (A×β, 167.4 in the corted vs 59.5 in the medulla, P<0.05) were found between the corted and the medulla, with also marked difference between the the corted-to-the medulla ratios of β and A (0.612 vs 0.078, P<0.05). Conclusion Contrast ultrasound of the kidney provides a useful means of renal circulatory flow study.