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脐带间充质干细胞治疗脑瘫51例疗效观察
引用本文:王金刚,尹忠民,闻华,王连仲,陈哲. 脐带间充质干细胞治疗脑瘫51例疗效观察[J]. 中国全科医学, 2011, 14(21)
作者姓名:王金刚  尹忠民  闻华  王连仲  陈哲
作者单位:1. 解放军第四六三医院神经外科,辽宁省沈阳市,110042
2. 深圳北科公司
摘    要:目的 总结分析脐带间充质干细胞治疗脑瘫的效果.方法 2009-2010年解放军第四六三医院神经外科应用脐带间充质干细胞治疗脑瘫患者229例,选择其中无智力障碍、一直进行康复治疗,近一年无明显进展的51例患者,进行日常生活活动能力(ADL)评估.比较治疗前与治疗1个疗程(21~28 d进行4次脐带间充质干细胞治疗)后ADL得分,评估疗效.结果 治疗前后ADL总分、步行动作、床上运动、认识交流动作得分比较,差异均有统计学意义(P<0.05).结论 脐带间充质干细胞对无智力障碍脑瘫患者治疗有效.

关 键 词:脑性瘫痪  间质干细胞移植  治疗

Application of Umbilical Cord Mesenchymal Stem Cells in Cerebral Palsy Treatment:Report of 51 Cases
WANG Jin-gang,YIN Zhong-min,WEN Hua,et al.. Application of Umbilical Cord Mesenchymal Stem Cells in Cerebral Palsy Treatment:Report of 51 Cases[J]. Chinese General Practice, 2011, 14(21)
Authors:WANG Jin-gang  YIN Zhong-min  WEN Hua  et al.
Affiliation:WANG Jin-gang,YIN Zhong-min,WEN Hua,et al.Department of Neurosurgery,the 463rd Hospital of PLA,Shenyang 110042,China
Abstract:Objective To review the effects of umbilical cord mesenchymal stem cells in treatment of cerebral palsy.Methods A total of 229 cases had received treatment with umbilical cord mesenchymal stem cells at our facility from 2009 to 2010,and 51 out of them,without mental retardation,had undergone rehabilitation therapy all the time,without significant progress in the past year,were enrolled,with their activities of daily living(ADL) assessed.ADL scores before treatment and one treating course(21~28 days,during w...
Keywords:Cerebral palsy  Mesenchymal stem cell transplantation  Treatment  
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