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重症急性胰腺炎合并呼吸衰竭患者腹腔感染危险因素及病原菌分析
引用本文:骆雪萍,叶宁,夏炳杰.重症急性胰腺炎合并呼吸衰竭患者腹腔感染危险因素及病原菌分析[J].中国全科医学,2011,14(21).
作者姓名:骆雪萍  叶宁  夏炳杰
作者单位:桂林医学院附属医院ICU,广西桂林市,541001
摘    要:目的 探讨重症急性胰腺炎(SAP)合并呼吸衰竭患者腹腔感染发生的危险因素及病原菌流行情况,为SAP的治疗提供依据.方法 回顾性分析2003年10月-2010年9月我院ICU收治的58例SAP合并呼吸衰竭患者的临床资料,根据临床表现及腹腔病原菌培养结果,分为腹腔感染(IAI)组及非感染(NI)组,比较两组急性生理学和慢性健康(APACHE)II评分、机械通气(MV)时间、腹内压、多器官功能障碍综合征(MODS)数≥3、外科干预率、连续肾脏替代治疗(CRRT)率及胆源性胰腺炎.调查IAI组病原菌流行情况.结果 SAP合并呼吸衰竭患者腹腔感染率为51.72%(30/58).MV时间、腹内压、外科干预是腹腔感染的独立危险因素.病原菌前10 d以革兰阴性杆菌为主,之后革兰阳性菌及真菌逐渐增加.结论 MV时间、腹内压及外科干预与SAP腹腔感染密切相关.SAP合并呼吸衰竭患者腹腔感染病原菌流行随病程的不同而变化.

关 键 词:胰腺炎  急性坏死性  呼吸功能不全  危险因素

Risk Factors and Distribution of Pathogens of Intra-abdominal Infection in Severe Acute Pancreatitis Complicated with Respiratory Failure
LUO Xue-ping,YE Ning,XIA Bing-jie.Risk Factors and Distribution of Pathogens of Intra-abdominal Infection in Severe Acute Pancreatitis Complicated with Respiratory Failure[J].Chinese General Practice,2011,14(21).
Authors:LUO Xue-ping  YE Ning  XIA Bing-jie
Institution:LUO Xue-ping,YE Ning,XIA Bing-jie.ICU,the Affiliated Hospital of Guilin Medical College,Guilin 541001,China
Abstract:Objective To investigate the risk factors and distribution of pathogens of intra-abdominal infection(IAI) in severe acute pancreatitis(SAP) complicated with respiratory failure in order to provide useful information for the treatment of SAP.Methods A total of 58 SAP patients with complicated respiratory failure who had received treatment at our facility from October 2003 to September 2010 were retrospectively reviewed and divided into the intra-abdominal infection(IAI) group and the non-infection(NI) group ...
Keywords:Pancreatitis  acute necrotizing  Respiratory insufficiency  Risk factors  
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