| 肺炎支原体感染和哮喘患儿血清IL-4和总IgE水平的研究 |
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| 引用本文： | 毛海英,曹兰芳,马敏. 肺炎支原体感染和哮喘患儿血清IL-4和总IgE水平的研究[J]. 上海交通大学学报(医学版), 2004, 24(8): 653-654 |
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| 作者姓名： | 毛海英 曹兰芳 马敏 |
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| 作者单位： | 上海第二医科大学仁济医院儿科,上海200001;上海第二医科大学仁济医院儿科,上海200001;上海第二医科大学仁济医院儿科,上海200001 |
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| 基金项目： | 上海市科委基金资助项目(004119050). |
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| 摘 要： | 目的 探讨肺炎支原体感染与支气管哮喘的相关性。方法 采用酶联免疫方法对60例肺炎支原体感染患儿,60例支气管哮喘患儿进行血清白细胞介素4(IL-4)及总IgE水平的测定,以30例正常者作为对照组。结果 肺炎支原体感染、支气管哮喘组血清IL-4和总IgE水平较正常对照组明显升高(P<0.01),支气管哮喘组又较肺炎支原体感染组显著升高(P<0.05)。结论 肺炎支原体感染与支气管哮喘在发病机制方面存在一定的相关性。
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| 关 键 词： | 肺炎支原体 支气管哮喘 白细胞介素4 总IgE |
| 文章编号： | 0258-5898(2004)08-0653-02 |
| 修稿时间： | 2003-08-18 |
Research of IL-4 and total IgE in mycoplasma pneumoniae infected and bronchial asthma attacking children patients |
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| MAO Hai-Ying,CAO Lan-Fang,MA Min. Research of IL-4 and total IgE in mycoplasma pneumoniae infected and bronchial asthma attacking children patients[J]. Journal of Shanghai Jiaotong University:Medical Science, 2004, 24(8): 653-654 |
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| Authors: | MAO Hai-Ying CAO Lan-Fang MA Min |
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| Abstract: | Objective This study was undertaken to discuss the relevance of mycoplasma pneumoniae infection and bronchial asthma. Methods We detected the IL-4 and the total IgE in 60 mycoplasma pneumoniae patients 60 bronchial asthma and 30 controls. Results The IL-4 and the total IgE of mycoplasma pneumoniae and bronchial asthma was significantly elevated compared to controls ( P<0.01); the level in the bronchial asthma patients was higher than mycoplasma pneumoniae infection group (P<0.05). Conclusion We found that there is some corre-lation between the pathogenesis of mycoplasma pneumoniae and bronchial asthma. |
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| Keywords: | mycoplasma pneumonias bronchial asthma interleukin- 4 total IgE |
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