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A Porcine Model for the Study of Liver Regeneration |
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| Abstract: | A technique of 65% partial hepatectomy in the pig is described. Thymidine kinase activity and mitotic index were used as indices of liver regeneration. Thymidine kinase activity increased from a baseline value of 1526 ± 256 to a maximum of 23992 ± 4966 dpm/mg protein on the third day after partial hepatectomy. The mitotic index also increased from 0–13.3 ± 1.66 on the third postoperative day. The indices of regeneration remained unchanged after sham operation |
| Keywords: | animal models bacterial adhesion biomaterials prosthetic infection Staphylococcus epidermidis |