Dynamic helical CT mammography of breast cancer |
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Authors: | Yamamoto Akira Fukushima Hitoshi Okamura Ryuji Nakamura Yoshiaki Morimoto Taisuke Urata Yoji Mukaihara Sumio Hayakawa Katsumi |
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Institution: | (1) Department of Radiology, Kyoto City Hospital, 1-2 Higashitakada-cho, Mibu, Nakagyo-ku, 604-8845 Kyoto, Japan;(2) Department of Surgery, Kyoto City Hospital, 1-2 Higashitakada-cho, Mibu, Nakagyo-ku, 604-8845 Kyoto, Japan;(3) Department of Pathology, Kyoto City Hospital, 1-2 Higashitakada-cho, Mibu, Nakagyo-ku, 604-8845 Kyoto, Japan |
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Abstract: | Purpose The purpose of this study was to determine whether dynamic helical computed tomography (CT)-mammography could assist in selecting
the most appropriate surgical method in women with breast cancer.
Materials and Methods Preoperative contrast-enhanced helical CT scanning of the breast was performed on 133 female patients with suspicion of breast
cancer at the same time as clinical, mammographic, and/or ultrasonographic examinations. The patients were scanned in the
prone position with a specially designed CT-compatible device. A helical scan was made with rapid intravenous bolus injection
(3 ml/s) of 100 ml of iodine contrast material. Three-dimensional maximum intensity projection (MIP) images were reconstructed,
and CT findings were correlated with surgical and histopathological findings.
Results Histopathological analysis revealed 84 malignant lesions and seven benign lesions. The sensitivity, specificity, and accuracy
levels of the CT scanning were 94.6%, 58.6%, and 78.9%. Helical scanning alone revealed additional contralateral carcinomas
in three of four patients and additional ipsilateral carcinomas in three of five patients. However, the technique gave false-positive
readings in 24 patients. The preoperative CT-mammogram altered the surgical method in six patients.
Conclusion Dynamic helical CT-mammography in the prone position may be one of the choices of adjunct imaging in patients with suspected
breast cancer scheduled for surgery. |
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Keywords: | breast neoplasms computed tomography cancer computed tomography helical computed tomography contrast enhancement |
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