常规超声定量评估骨龄

目的 与X线评估骨化率（OR）对比，评价常规超声评估标准骨龄（BA）的价值及其简易方法。方法 对215例患者（男88例，女127例）于1周内先后行左手及腕部X线检查和超声检查，测量桡骨、尺骨，第1、3、5掌骨，第1、3、5近节指骨，第3、5中节指骨及第1、3、5远节指骨共13块骨骼的骨化中心及骨骺长径，计算各目标骨骨化中心与骨骺长径之比，获得其OR及BA，分析OR与BA的相关性。结果 男、女性患者各目标骨的OR与BA呈中-高度相关（r_男为0.77~0.94，r_女为0.77~0.93，P均<0.001），13块骨骼的OR总和与BA呈高度相关（r_男=0.96，r_女=0.96，P均<0.001），桡骨、尺骨OR总和与BA呈高度相关（r_男=0.95，r_女=0.95，P均<0.001）。结论 常规超声具有定量评估BA的潜在价值；仅测量桡骨及尺骨或可作为超声评估BA的简易方法。

Conventional ultrasound for quantitative evaluation on bone age

Objective To explore the potential value of conventional ultrasound for evaluating bone age (BA) compared with ossification ratio (OR) measured on X-ray films, and to observe the feasibility of simple method ultrasonic evaluation of BA. Methods A total of 215 patients (88 males, 127 females) underwent X-ray examination and ultrasonography of left hand and left wrist within 1 week. The distal end of radius and ulna, the 1st, 3rd, 5th metacarpal, 1st, 3rd, 5th proximal phalanx, 3rd, 5th middle phalanx and 1st, 3rd, 5th distal phalanx were assessed with ultrasound. The ratio of diameters of the ossification center and epiphysis was calculated to obtain OR of each target bone. The correlation of OR and BA was analyzed. Results OR of target bones were moderately or highly correlated with BA (r_male was 0.77-0.94, r_female was 0.77-0.93, all P<0.001). The sum of OR of all 13 bones was highly correlated with BA (r_male=0.96, r_female=0.96, both P<0.001), while of the radius and ulna were highly correlated with BA (r_male=0.95, r_female=0.95, both P<0.001). Conclusion Conventional ultrasound had potential value in quantitative evaluation of BA. Measuring only radius and ulna might become a simple method for ultrasonic assessment of BA.